Highfield were beaten finalists last season and will be aiming to overcome the favourites and deny their rivals another league and cup double.
UL Bohemians beat Ballincollig, Tralee and Blackrock on the road to the final, while Highfield have accounted for Portlaoise, Nenagh Ormond and Old Belvedere.
In the Plate final Portlaoise, home club of top try scorer Alison Miller, take on St. Mary's College.
Women's All-Ireland Plate Final - Clanwilliam RFC, Saturday April 6th.
Portlaoise v St. Mary's College, 1:00pm
Women's All-Ireland Cup Final - Clanwilliam RFC, Saturday April 6th
Highfield v UL Bohemians, 3:00pm