The first semi-final will start at 7.05pn on Friday, May 13, with the second one kicking-off at 6.30pm the next day, Saturday, May 14.
There are five rounds of the regular Magners League to go now that the RBS 6 Nations has come to a conclusion and there is still all to play for in one of the most competitive league seasons on record.
Table-topping Munster have a nine-point lead over reigning champions, the Ospreys, in second at present, but the 2003 and 2009 winners still have to travel to Wales twice in the closing stages to meet both the Ospreys and Cardiff Blues.
Munster also have to host arch rivals Leinster and Connacht at home in a run-in that could still see them come under pressure for the top spot and a guaranteed home tie in the semi-finals.
The top two finishers in the regular Magners League season will enjoy home advantage in the semi-finals - 1 v 4 and 2 v 3 - the grand final will be played at the home venue of the highest ranked team reaching last two.
Celtic Rugby chairman Andy Irvine said: "We have an incredible final five rounds to go in the Magners League and it is anyone's guess who will fill the top four places.
"There are still seven sides within striking distance and the battle for home advantage is set to go down to the wire.
"We have some world class fixtures to come before the end of the regular season and then three fantastic matches to determine who will follow the Ospreys as the grand final champions.
"It has been the Ospreys' stated intention from the start of the season to become the first team to successfully defend the Magners League crown and they are well in the mix at the moment in second place and with a home game to come against Munster.
"The 2009 champions, Leinster, who are still in the race for Heineken Cup glory along with Ulster, are lurking in third and there are quality teams preparing for their final assault over the next few months.
"While every one of the 12 teams can still have an influence on the final shape of the top-four teams, they can't all make it.
"However, there is still national pride and World Cup places to be played for over the final five rounds of the regular season."
MAGNERS LEAGUE PLAY-OFF MATCHES:
Friday, May 13, 7.05pm
Saturday, May 14, 6.30pm
Grand Final -
Saturday, May 28, 5.05pm