JohnKelly and Barry Murphy have lost their respective battles to be fit forMunster's Heineken Cup Pool 4 trip to Cardiff on Sunday (Arms Park,kick-off 1pm).
Thepair were injured in last week's Magners League win over Connacht -Kelly sustained a hamstring injury, while Murphy left Thomond Park witha damaged shoulder - but there is better news regarding David Wallace. The Ireland flanker has recovered from the leg injury he picked up against Connacht and will start this weekend.
In all, coach Declan Kidney has made seven changes, two of them positional, to the side that beat Connacht 13-0.
In the forwards, Marcus Horan's absence due to a calf injury sees Federico Pucciariello switch from tighthead to loosehead prop, John Hayes is back in the number three jersey while Cork Constitution youngster Darragh Hurley, who was the starting loosehead last time out, will provide prop cover on the bench.
The rest of the pack is unchanged, meaning back rowers Wallace and Alan Quinlan will win their 50th Heineken Cup caps from the start on Sunday.
This is one position on the replacements bench to be filled withCullen, Mossie Lawlor and Portuguese international Diogo Mateus all vyingfor it.
MUNSTER: Shaun Payne; IanDowling, Lifeimi Mafi, Trevor Halstead, Anthony Horgan; Ronan O'Gara,Peter Stringer; Federico Pucciariello, Frankie Sheahan, John Hayes,Donncha O'Callaghan, Paul O'Connell (capt), Alan Quinlan, DavidWallace, Denis Leamy.
Replacements: Andy Kyriacou, Darragh Hurley, Chris Wyatt, John O'Sullivan, Tomas O'Leary, Jeremy Manning, AN Other.