The six seeded teams were last season's champions Wasps, Stade Francais, Leinster, Benetton Treviso, Glasgow and the Ospreys.
Ulster were drawn in Pool 2, alongside the Ospreys, Gloucester and Bourgoin, while Munster have Wasps, Clermont Auvergne and Llanelli to contend with in Pool 5.
Leinster, who, like Munster, reached last season's Heineken Cup quarter-finals, have been pitted with Leicester Tigers, Toulouse and Edinburgh in Pool 6, which is arguably 'the group of death' with Tigers and Toulouse having won the competition on five occasions between them.
The first round of pool fixtures will take place between November 9 and 11, with the final in May 2008.
Further details to follow...
2007/08 HEINEKEN CUP POOL DRAW:
Benetton Treviso, London Irish, USA Perpignan, Newport Gwent Dragons
Ospreys, Gloucester Rugby, Bourgoin, ULSTER RUGBY
Stade Francais Paris, Bristol Rugby, Cardiff Blues, Harlequins
Glasgow Warriors, Saracens, Biarritz Olympique, Viadana
London Wasps, Clermont Auvernge, Llanelli Scarlets, MUNSTER
LEINSTER, Leicester Tigers, Toulouse, Edinburgh Rugby
- Seeded teams in bold