Leo Cullen misses the game through injury, but the squad has a strong look to it for the penultimate clash of the campaign.
Bernard Jackman is included in the squad fresh from being named the Bank of Ireland Leinster Player of the Year.
In all, Leinster coach Michael Cheika has 11 Ireland internationals at his disposal in the squad.
Tickets for Saturday's match have passed the 15,000 mark and supporters are urged to book early online at the Leinster website to avoid disappointment.
LEINSTER Squad (v Newport Gwent Dragons): Backs (13) - Chris Keane, Chris Whitaker, Jonathan Sexton, Christian Warner, Rob Kearney, Michael Berne, Felipe Contepomi, Brian O'Driscoll, Gary Brown, Luke Fitzgerald, Shane Horgan, Girvan Dempsey, Felix Jones.
Forwards (14) - Cian Healy, Ollie Le Roux, Brian Blaney, Bernard Jackman, Stephen Knoop, Stan Wright, Trevor Hogan, Cameron Jowitt, Malcolm O'Kelly, Devin Toner, Stephen Keogh, Keith Gleeson, Shane Jennings, Jamie Heaslip.