Ulster will meet stiff resistance from a Glasgow side who returned to winning ways with their 38-21 victory over the Scarlets last time out.
Also on Friday it is the battle of the capital city teams as Edinburgh host Leinster at Murrayfield, a ground where the home team has not lost in their last six Magners League outings.
The two teams have met on three occasions already this season - once in the Magners League and twice in the Heineken Cup - with Leinster victorious each time, and their confidence is bound to be high following their success in Europe last weekend.
Saturday sees a West Wales derby when the Ospreys travel to Llanelli to face the Scarlets at the Parc y Scarlets.
The Ospreys will be hoping to put an end to their poor run of form that has seen them win just one of their last four matches - 16-13 in Ulster on April 3.
The Scarlets will face them with confidence having won their last four home games against fellow Welsh regions.
The round wraps up with the all-Ireland clash between Munster and Connacht at a sold-out Thomond Park, also on Saturday.
Connacht turned over Munster 12-6 at the Sportsground on December 28 but have never managed to achieve back-to-back wins over their illustrious neighbours.
Munster will be tough opponents and are in a rich vein of form as shown in their impressive European quarter-final victory over the Ospreys last Sunday.
MAGNERS LEAGUE - ROUND 15 FIXTURES:
Friday, April 17 -
Glasgow Warriors v ULSTER, Firhill Arena, 7.30pm
Edinburgh v LEINSTER, Murrayfield, 7.45pm (live Setanta Sports Ireland/Setanta Sports 2)
Saturday, April 18 -
Scarlets v Ospreys, Parc y Scarlets, 5.30pm (live S4C/Setanta Sports Ireland)
MUNSTER v CONNACHT, Thomond Park Stadium, 7.30pm (live Setanta Sports Ireland/Setanta Sports 2)