There are two further games on Friday evening, Benetton Treviso hosting Glasgow Warriors and the Scarlets facing their Welsh rivals, the Newport Gwent Dragons.
Both games will be broadcast live, by Mediaset and BBC Wales respectively, while Scottish fans who cannot travel to Italy should be able to follow their team's progress thanks to BBC ALBA's coverage.
Round 21 opens in Italy on Thursday, May 1, the Mayday holiday in most of Europe, when Zebre host the Ospreys - again to be shown by Mediaset.
Finally there are two games on Saturday, May 3, Cardiff Blues travelling to the Sportsground to take on Connacht, and Edinburgh hosting Munster at their alternative venue of Meggetland, a game that will be shown on both BBC ALBA and TG4.
For full details including the broadcast schedule, click here.