Miah Nikora, making his first appearance this season, was therefore called upon to act as the replacement number 9 against Zebre. O'Donohoe remains unavailable to play this week against Benetton Treviso.
It has been confirmed that hooker Sean Henry, who has been struggling with a neck injury in recent weeks, will undergo surgery. The 26-year-old from Sligo is expected to be unavailable for the remainder of the season but the timing of the surgery will allow him to return for pre-season training in June.
Meanwhile, Pat Lam and his coaching staff received a boost this week with the news that forwards Nathan White and Eoin McKeon are now both available for selection as the province aim for their third league win on the trot.
Robbie Henshaw will continue to train with the Ireland squad, but will return to his province ahead of the game on Saturday.
The Connacht team to face Treviso is set to be announced on Friday. The round 16 tie will not be televised so the only way to see the action is to get down to the Sportsground.
Tickets for Connacht v Treviso are available online from tickets.ie, from the Connacht Rugby office and from Centra and SuperValu stores province-wide.
Connacht Rugby is also delighted to launch their 'Strength in Numbers' campaign this week. The province will hold a celebration of Women's rugby at the Connacht v Treviso game on Saturday evening.
This date was specifically chosen to coincide with International Women's Day and the Ireland Women's team's historic debut appearance at the Aviva stadium the following weekend.
The event will involve a series of player interviews, information stands for potential recruits, and some informal introductory skills sessions, and should help propel Women's rugby firmly into the local spotlight.