12 Dec, 14:42
Prop Cian Healy is expected to miss the start of the 2014 RBS 6 Nations after undergoing surgery on his injured ankle on Wednesday.
Three of the changes come in the backline and one in the backrow where Cardiff's Semo Sititi is preferred to Patrick Segi.
Va'aiga Tuigamala replaces try scorer from last Sunday, Silao Leaega, Brian Lima comes in to partner Tuigamala in centre at the expense of Too Vaega and Afato So'oalo comes in on the left wing.
Samoa. Tanner Vili; Lome Fa'atau, Brian Lima, Va'aiga Tuigamala, Afato So'oalo; Earl Va'a, Steven So'oalo; Tamato Leupolu, Jonathon Meredith Jeremy Tomuli; Kition Viliamu; Opeta Palepoi; Sioosi Vaili, Semo Sititi, George Stowers.
Replacements: Mahonri Schwalger, Faamaoni Laomilo, Alfie To'oala, Patrick Segi, Denning Tyrell, Too Vaega, Silao Leaega.