Former Wallaby scrum half Chris Whitaker is also named in a freshened up squad which sees the likes of Gary Brown, Ronan McCormack, Kevin McLaughlin and Michael Berne also included after their outings for the Leinster 'A' team in recent weeks.
Michael Cheika will confirm his team and replacements for the Rodney Parade tie on Thursday.
Meanwhile, over 5,500 supporters have renewed their Leinster Season Tickets for next season and this year's figure of approximately 7,500 looks set to be eclipsed over the coming weeks with tickets continuing to sell fast.
Leinster Season Ticket prices start at 219 euro and for further information visit the province's website.
Tuesday saw three Leinster players - Brian O'Driscoll, Shane Horgan and Bernard Jackman - visit Bank of Ireland HQ in Dublin with the Magners League trophy. For photos of the players' question and answer and signing session, please click here.
LEINSTER Squad (v Newport Gwent Dragons): Backs (13) - Chris Keane, Chris Whitaker, Jonathan Sexton, Christian Warner, Luke Fitzgerald, Michael Berne, Brian O'Driscoll (capt), Gary Brown, Shane Horgan, Girvan Dempsey.
Forwards (14) - Cian Healy, Ronan McCormack, Brian Blaney, Bernard Jackman, Juan Francisco Gomez, Stephen Knoop, Trevor Hogan, Cameron Jowitt, Malcolm O'Kelly, Devin Toner, Shane Jennings, Stephen Keogh, Richie Leyden, Kevin McLaughlin.