Castres Olympique prop Ramiro Herrera is the only newcomer in a largely domestic-based Argentina team named to face Ireland in Saturday's first Test in Resistencia (kick-off 3.40pm local time/7.40pm Irish time).
Ramiro Herrera will make the step up to international rugby just a week after playing in Castres' Top 14 Championship final defeat to Toulon.
The 25-year-old Herrera, who stands at 6ft 3in and weighs over 19 stone, is one of three overseas players in the team selected by head coach Daniel Hourcade, who was appointed in October.
Nicolás Sánchez, who plays for Bordeaux-Bègles in France, will start at out-half alongside captain Martin Landajo, while lock Manuel Carizza from South African outfit the Stormers is the most experienced player in the squad with 40 caps.
The Argentina team also include four players who have won their first caps during the past year - prop Lucas Noguera Paz and centre Jerónimo de la Fuente made their Test bows last month, with winger Santiago Cordero a debutant last November and lock Tomas Lavanini's first game coming against South Africa last August.
Hourcade's charges may lack experience but they have played two recent matches in the South American Championship, running in 10 tries - including four for winger Manuel Montero - during a 65-9 hammering of Uruguay on May 17.
A week later, the Pumas went one better, notching 11 tries as they coasted to a 73-12 win over Chile.
Of the team that started that day in Santiago, full-back Joaquin Tuculet, centre Gabriel Ascarate and the half-backs are retained along with Lavanini in the second row.
Saturday's first Test will be broadcast live on Sky Sports 1 HD (coverage begins at 7.30pm). The teams will play for the Admiral William Brown Cup which is named in memory of the Irish-Argentine Navy admiral William Brown.
ARGENTINA Team & Replacements (v Ireland, Estadio Centenario, Resistencia, Chaco, First Test, Saturday, June 7, kick-off 3.40pm local time/7.40pm Irish time):
15. Joaquin Tuculet (Unattached) 8 14. Santiago Cordero (Regatas Bella Vista) 5 13. Jerónimo de la Fuente (Duendes RC) 2 12. Gabriel Ascarate (Natación y Gimnasia) 12 11. Manuel Montero (Pucará) 10 10. Nicolás Sánchez (Bordeaux-Bègles) 18 9. Martín Landajo (CASI) 28 (capt) 1. Lucas Noguera Paz (Lince RC) 2 2. Matías Cortese (Liceo RC) 5 3. Ramiro Herrera (Castres Olympique) * 4. Manuel Carizza (Stormers) 40 5. Tomas Lavanini (Hindú Club) 5 6. Rodrigo Baez (Liceo RC) 8 7. Tomás de la Vega (CUBA) 9 8. Benjamin Macome (Unattached) 17
16. Julian Montoya (Club Newman) 2 17. Bruno Postiglioni (La Plata RC) 10 18. Nahuel Tetaz Chaparro (La Plata RC) 5 19. Matías Alemanno (La Tablada) 2 20. Javier Ortega Desio (Estudiantes de Paraná) 5 21. Tomás Cubelli (Belgrano Athletic) 22 22. Santiago González Iglesias (Asociación Alumni) 4 23. Lucas González Amorosino (Oyonnax) 30
Jamie Heaslip will captain the Ireland XV against the Barbarians at Thomond Park on Thursday. He spoke to Irish Rugby TV about facing the star-studded visitors and the battle he is relishing with his Leinster colleague Shane Jennings, who captains the Baa Baas.
Ireland Under-20 head coach Nigel Carolan has likened the World Rugby Under-20 Championship to 'a mini Six Nations in three weeks'. His side take on Argentina in their tournament opener in Parma next Tuesday.
Ireland Under-20 backs Nick McCarthy and Garry Ringrose and Feargal O'Rourke from team sponsors PwC spoke to Irish Rugby TV as the squad prepare for the World Rugby U-20 Championship which starts next week in Italy.
We caught up with Sean O'Brien at the Canterbury Ireland training kit launch where he spoke about next week's Barbarians game, the build-up to the Rugby World Cup and 'moving forward' with Leinster next season.
We caught up with Ireland international Luke Fitzgerald at the launch of the new Canterbury Ireland training kit. He spoke about his recovery from shoulder surgery and his aim to be fit for the Guinness Summer Series games in August.
Ireland Men's Sevens squad member Matthew D'Arcy is gearing up for a 'long and tough season' of Sevens rugby this summer. "It's very exciting (to be involved), there's a huge opportunity for us all," he said.
IRFU Director of Sevens and head coach Anthony Eddy talks about the Ireland Men's Sevens squad's upcoming tournaments and ambitions, while squad members Cian Aherne and Tom Daly tell us about their enthusiasm to play Sevens for Ireland.
IRFU Performance Director David Nucifora speaks about the newly-announced Ireland Men's Sevens squad and structures, and we also hear from squad member Matthew D'Arcy on the training camps and how he got involved.
IRFU Women's Rugby Ambassador Fiona Coghlan played in three Rugby World Cups and captained Ireland to Grand Slam glory. She believes the 2017 Women's World Cup in Ireland will be a 'hugely successful and exciting' tournament.
Thrilled that the 2017 Women's Rugby World Cup will be held on home soil, Ireland head coach Tom Tierney says there will be 'a lot of planning from a coaching and player point of view so that we give it our best shot and leave everything out on the field in 2017'.
They needed a 27-point winning margin against Scotland. They got that and more. The Ireland Women's team captured their second Women's RBS 6 Nations title in style at Broadwood Stadium - relive their Championship winning day in our exclusive video.