Robbie Henshaw, who was on international duty last week, is named at full-back for his 21st senior appearance for the province.
The 27-year-old Brian Murphy, who made his Connacht debut in Cardiff, will start again at inside centre in a midfield partnership with fellow Galway native Eoin Griffin.
Skipper Gavin Duffy is named on the left wing, replacing Fetu'u Vainikolo who drops to the replacements bench.
Dan Parks was a late withdrawal for the Cardiff game with a hamstring injury. He will return to out-half duties, taking over from the benched Miah Nikora.
Meanwhile, there is just one change up front with Michael Kearney replacing Michael Swift in the second row.
Swift sustained a knee injury during training earlier in the week. Connacht's most-capped player is waiting on scan results to determine the severity of the injury.
A recent returnee from injury, George Naoupu, is listed on the bench along with front rowers Adrian Flavin, Ronan Loughney and Denis Buckley.
CONNACHT (v Zebre): Robbie Henshaw; Danie Poolman, Eoin Griffin, Brian Murphy, Gavin Duffy (capt); Dan Parks, Kieran Marmion; Brett Wilkinson, Jason Harris-Wright, Nathan White, Michael Kearney, Andrew Browne, John Muldoon, Willie Faloon, Eoin McKeon.
Replacements: Adrian Flavin, Denis Buckley, Ronan Loughney, Thomas Anderson, George Naoupu, Paul O'Donohoe, Miah Nikora, Fetu'u Vainikolo.