Tiernan O'Halloran, who came on from the bench against Zebre last Saturday, starts on the right wing with Danie Poolman named amongst the replacements.
The pack remains unchanged with Michael Swift captaining the side for their first away trip of the season and the first game on Cardiff's newly installed artificial pitch at the Arms Park.
Experienced flanker John Muldoon celebrates his 200th Connacht cap in the Welsh capital on Friday night. The game is live on both TG4 and BBC 2 Wales.
CONNACHT (v Cardiff Blues): Gavin Duffy; Tiernan O'Halloran, Robbie Henshaw, Eoin Griffin, Matt Healy; Dan Parks, Kieran Marmion; Brett Wilkinson, Jason Harris-Wright, Nathan White, Michael Swift (capt), Andrew Browne, John Muldoon, Willie Faloon, George Naoupu.
Replacements: Sean Henry, Rodney Ah You, Ronan Loughney, Aly Muldowney, Jake Heenan, Paul O'Donohoe, Craig Ronaldson, Danie Poolman.