This will be the first time the world famous tournament has kicked off on a Friday night, though Wales and France have played each other during the Championship in recent seasons on a Friday.
Ireland will open their 2011 campaign with a trip to Italy on Saturday, February 5. France will play Scotland later that day in Paris.
The first RBS 6 Nations game at the Aviva Stadium will take place a week later on Sunday, February 13, with France providing the opposition.
There is a free weekend after that before the Championship resumes with Ireland again playing on a Sunday, this time against Scotland at Murrayfield.
Another free week in March is followed by a Saturday evening trip for Declan Kidney's men to the Millennium Stadium to play Wales.
The 'Super Saturday' final day of the Championship sees Scotland at home to Italy and France at home to Wales either side of Ireland's last game - an evening kick-off against England at the Aviva Stadium.
2011 RBS 6 NATIONS CHAMPIONSHIP FIXTURES:
- All kick-off times are local
Friday, February 4
Wales v England, Millennium Stadium, 7.45pm
Saturday, February 5
Italy v IRELAND, Stadio Flaminio, 3.30pm (2.30pm Irish time)
France v Scotland, Stade de France, 6pm
Saturday, February 12
England v Italy, Twickenham, 2.30pm
Scotland v Wales, Murrayfield, 5pm
Sunday, February 13
IRELAND v France, Aviva Stadium, 3pm
Saturday, February 26
Italy v Wales, Stadio Flaminio, 3.30pm
England v France, Twickenham, 5pm
Sunday, February 27
Scotland v IRELAND, Murrayfield, 3pm
Saturday, March 12
Italy v France, Stadio Flaminio, 3.30pm
Wales v IRELAND, Millennium Stadium, 5pm
Sunday, March 13
England v Scotland, Twickenham, 3pm
Saturday, March 19
Scotland v Italy, Murrayfield, 2.30pm
IRELAND v England, Aviva Stadium, 5pm
France v Wales, Stade de France, 8.45pm