Up front, BJ Botha and Bryan Young start either side of newcomer Andy Kyriacou at hooker, while there is also a first start for Dan Tuohy who partners Ryan Caldwell in the province's second row.
Chris Henry, Willie Faloon and Robbie Diack will make up an all-action back row with an average age of just 24.
Scrum half Isaac Boss captains the side and links up with Ian Humphreys at half-back, while recent Ireland caps Ian Whitten and Darren Cave will rekindle their burgeoning centre partnership, backed up with an experienced back-three of Simon Danielli, Clinton Schifcoske and Bryn Cunningham.
Tickets for the match are available from as little as £10 for adults and £5 for kids and can be purchased online at www.ulsterrugby.com, from the Ravenhill Ticket Office or over the Ticketline on 028 9049 3222 (Option 2).
ULSTER (v Newcastle Falcons): Bryn Cunningham; Clinton Schifcoske, Darren Cave, Ian Whitten, Simon Danielli; Ian Humphreys, Isaac Boss (capt); Bryan Young, Andy Kyriacou, BJ Botha, Dan Tuohy, Ryan Caldwell, Chris Henry, Willie Faloon, Robbie Diack.
Replacements: Nigel Brady, Declan Fitzpatrick, Neil McComb, Thomas Anderson, Paul Marshall, Niall O'Connor, Nevin Spence.