The 21-year-old flanker started against New Zealand in Tokyo recently before coming on as a replacement during last Saturday's 18-9 Cook Cup win over England at Twickenham.
The change in the back row aside, the Australian line-up is unchanged with Queensland Reds duo Quade Cooper and Digby Ioane linking up again in midfield.
The side will be led for just the third time by Rocky Elsom, the former Leinster flanker makes his return to Dublin as the captain of his country.
Australia coach Robbie Deans said: "Getting a result against England last weekend was a great confidence booster for the whole squad, but we know that the standard we produced last week won't be good enough against this Irish team.
"There was an uncertainty about England, in terms of the transitional nature of their development as a team, that doesn't pertain to Ireland.
"The Irish are an established and experienced combination who are used to winning and expect to win every time that they play."
AUSTRALIA TEAM & REPLACEMENTS (v Ireland, GUINNESS Series 2009, Croke Park, Sunday, November 15, kick-off 3pm):
15 - Adam Ashley-Cooper (Brumbies)
14 - Peter Hynes (Queensland Reds)
13 - Digby Ioane (Queensland Reds)
12 - Quade Cooper (Queensland Reds)
11 - Drew Mitchell (NSW Waratahs)
10 - Matt Giteau (Brumbies)
9 - Will Genia (Queensland Reds)
1 - Benn Robinson (NSW Waratahs)