Ireland's third game of the new international season will see Declan Kidney's men battle it out with South Africa in the clash of the champions - the Grand Slam winners against the reigning World Cup and Tri Nations champions - at Croke Park (kick-off 2.30pm).
The last time the Springboks visited Dublin in November 2006, they fell to a 32-15 defeat as tries from Andrew Trimble, Marcus Horan, Shane Horgan and David Wallace helped Ireland roar to victory at Lansdowne Road.
Can the men in green make it three wins in-a-row against the mighty 'Boks? 2004, 2006 and 2009?
O2 MatchDay Live also features live audio feeds of match commentary from RTE Radio and BBC Radio Ulster.
Every ruck, every maul, every try right here on IrishRugby.ie with O2 MatchDay Live.
For more on the build-up to the game, visit our dedicated GUINNESS Series tournament page featuring multimedia interviews, head-to-head details, training pics and much more - click here.