Defending champions Cork Constitution face a tough trip to Stradbrook to face second-placed Blackrock with Garryowen, Dolphin and Shannon breathing down their necks!
In the middle of the table the scrap for a coveted top eight finish to secure a place in Division 1A next season continues.
Belvo, 'Wegians and Ballymena will all be hoping to capitalise on any potential slip-ups by UL Bohs or St. Mary's College.
In Division Two, the top two sides, UCC and Lansdowne, are away to Greystones and Highfield respectively while fifth-placed Bruff will be hoping to put one over on third-placed Ballynhinch, who may have one eye on the AIB Cup final the following weekend.
Division Three leaders Corinthians are away to bottom-of-the-table Waterpark and will be hoping consolidate their lead over the likes of Old Wesley and Midleton.
After the drama of the Grand Slam last weekend, it is a chance to get out and see the stars of tomorrow and the stalwarts of the game in top class club action.
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