"It's the same as I always see it against Scotland, particularly at Murrayfield. Very tough, very physical, uncompromising. A tight game," O'Driscoll said.
"I think I've played here three or four times for Ireland and it's always been tough. Scotland are always tough, people probably don't give them the credit that they deserve. They always make it really hard for you."
Ireland needed two late penalty goals from Ronan O'Gara to earn a 19-18 win over their last Championship visit to Murrayfield.
That victory saw O'Driscoll lift the Triple Crown trophy but all talk of possible silverware this year has been brushed to one side.
Meanwhile, Kidney insisted that his side will have to work hard for their points against Scotland as the hosts' defence is an area they are particularly strong in.
"We're going to have to play smart. Their defence is getting better," he said.
"They conceded no tries against Italy, in the match before that it was just one and before that (against Wales) it was the sin-bin that was the difference.
"This is only my first year, but these matches don't get easier."
Click here to view photos from the Captain's Run training session at Murrayfield.