Phoenix Ulster Rugby Academy players Ian Whitten, Tommy Seymour and Willie Faloon have all been named in the starting line-up, while two more Academy members, Johnny Shiels and Paul Karayiannis, will start the match on the bench.
Back from World Cup Sevens duty with Ireland, Paul Marshall will provide cover for Cillian Willis at scrum half.
Speaking about Friday's game, Ulster 'A' coach Gary Longwell said: "We have had a good run in the season so far, winning all of our games apart from our last meeting with Munster.
"Now we are on home soil, we will be looking for that all important victory. The team has a great mix of ability and experience and we plan to use the resources we have, tactically and skilfully, to achieve a convincing win over Munster tomorrow."