The AIB Cup this season saw last year's winners Ballynahinch knocked out in the second round by the very team they beat in the 2008/09 final, Cork Constitution.
The Cork side, who also won the inaugural AIB Cup in 2006, will play Ballymena away at Eaton Park this Saturday.
The other AIB Cup semi-final is an all-Munster affair, with Dolphin at home to Garryowen as the two Division 1A teams battle it out for a place in the Dubarry Park decider.
The AIB Junior Cup semi-finals also take place this weekend with Tullamore, the defending champions, aiming for a third final appearance in-a-row as they take on Armagh at home.
Galway club Monivea play at home and are also looking to topple an Ulster side as they host City of Derry.
Full previews of all the AIB Cup and AIB Junior Cup semi-finals are available to view here.