It promises to be a fascinating game with Leinster set to perform in the extraordinary circumstances of a sell-out Lansdowne Road - a huge tribute to the hard work of Leinster Chief Executive Michael Dawson - and with the partisan crowd behind them Leinster will be at short-odds with the bookies to make it through to the semi-final.
Not that Matt Williams will be in any way complacent about the task his side faces. Biarritz are a good side who have, unlike Leinster, been playing regularly over the past number of weeks, they are at full strength and will relish the opportunity of setting up a semi against Perpignan back home.
Leinster. G Dempsey; D Hickie, B O'Driscoll (capt), D Quinlan, G D'Arcy; C Warner, B O'Meara; E Byrne, S Byrne, P Coyle, L Cullen, M O'Kelly, E Miller, V Costello, K Gleeson.
Biarritz Olympique. N Brusque; P Bernat-Salles, M Stcherbina, J Isaac, P Bidabe; J Peyrelongue, D Yachvilli; M Fitzgerald, J-M Gonzalez (capt), D Avril, D Couzinet, O Roumat, S Betsen, T Lievremont, C Milheres.Replacements: J Campo, B Gallais, O Nauroy, O Tonita, L Mazas, G Bousses, M Etcheverria.
Referee: S Lander (Eng).
(For all the latest on the game go to www.leinsterrugby.ie)