When these teams met in Dublin twelve months ago, first half tries fom Jamie Heaslip and Tomas O'Leary helped Ireland claim a 29-11 victory. Ronan O'Gara kicked 16 points on the day.
We will have live text commentary of Ireland's first match of the 2011 Championship direct from Rome, with winger Fergus McFadden making his senior debut, Luke Fitzgerald featuring at full-back for the second time and Mike Ross and Sean O'Brien both starting for the first time in the Six Nations.
Plug in the laptop or turn on the PC and enjoy a flavour of this afternoon's game live on IrishRugby.ie with thanks to O2, sponsors of MatchDay Live.
There will be full live text and score updates throughout the coverage as Ireland look to continue their winning ways against the Azzurri - that is 11 wins in 11 Six Nations encounters so far.
We provide links to the live radio commentary from the RTE Radio 1 and BBC 5Live teams, with coverage also available on RTE Two and BBC One Television.
Starting at 2pm with our pre-match build-up (the game kicks off at 2.30pm Irish time/3.30pm Italian time), you can feel part of the action on IrishRugby.ie with MatchDay Live.
Look out for the MatchDay Live button in the Ireland section or simply click on the link below: