The game will start from the first match on Friday, February 4 and will run through to the final match of the RBS 6 Nations on Saturday, March 19.
You will receive a fantasy budget to create your own 'Fantasy Rugby Team' of players in the tournament.
Your fantasy team will then receive fantasy oints for the real life performances of your selected players.
Prizes will be awarded throughout the competition including team of the week manager, who will win an Ireland rugby jersey.
The overall winner of Guinness Fantasy Rugby will win a trip to New Zealand to follow Ireland.