Having won two matches so far this season at the Aviva Stadium against Munster (Magners League) and Clermont Auvergne (Heineken Cup), the Board is confident that this decision will give the opportunity to the greatest number of Leinster supporters to see the game.
Full ticket details for the Heineken Cup quarter-final will be available in the coming days once the kick-off time and date have been confirmed by ERC, the tournament organisers.
Leinster Chief Executive Mick Dawson commented: "I would firstly congratulate the entire squad and management on reaching the quarter-finals in what was, arguably, the toughest pool that the province has ever faced.
"To reach the knockout stages - and achieve a home quarter-final draw in the process - is an impressive achievement and due reward, not only for the squad, but also for our loyal supporters.
"The fans have followed the side across Europe at great expense and also established their own reputation as a significant element in the Leinster quest to regain the Heineken Cup.
"They once again added to this reputation last Friday night when over 1,000 supporters made the trip to Paris and gave wonderful vocal support throughout the game (against Racing Metro 92).
"In our two fixtures at the Aviva Stadium to date, we have enjoyed two outstanding spectacles with the team having been inspired to victory by close to 100,000 supporters over the course of both games.
"Existing Leinster season ticket holders will be offered the priority option to purchase tickets for this game and information will be circulated shortly. There will also be a range of family packages and junior tickets on public sale.
"We will continue the increasingly popular 'One Province' scheme as we do for all of our home matches, a community ticketing initiative designed specifically for underage groups travelling to matches at discount prices."
He added: "We remain committed to our home at the RDS, but given the manner in which our Leinster supporter base has grown in recent years, we believe that we have a duty to cater for as large an audience as possible for special one off matches such as this, which will be a local and international event.
"I would like to thank Martin Murphy and his team for facilitating our plans to play at the Aviva Stadium, a venue which is fast becoming one of the leading arenas in Europe.
"Over the coming days we will finalise competitive ticket prices, mindful of the difficult economic climate and the great commitment of our supporters, both at home and abroad, over recent seasons."