In the backs there are two changes in personnel. Andrew Trimble, who has recovered from a finger injury, comes onto the left wing in place of Denis Hickie.
The other back-line change sees Eoin Reddan named at scrum half in place of Peter Stringer. Reddan, who won a Heineken Cup medal this year with Wasps, will make his fourth start for Ireland having previously appeared as a replacement against France in 2006 and against Scotland last month. He got his first full start against Argentina on the recent summer tour.
In the pack, Jerry Flannery makes his first start of the tournament at hooker instead of Rory Best. Best picked up a thumb injury on Saturday and will be out for up to three weeks.
There are also two changes to the replacements, with Frankie Sheahan and Gavin Duffy being named in the matchday 22.
IRELAND TEAM & REPLACEMENTS (v France, Stade de France, Friday, September 21, kick-off 9pm local time):
15 â00 Girvan Dempsey (Terenure College/Leinster)
14 â00 Shane Horgan (Boyne/Leinster)
13 â00 Brian Oâ00Driscoll (UCD/Leinster) captain
12 â00 Gordon Dâ00Arcy (Lansdowne/Leinster)
11 â00 Andrew Trimble (Ballymena/Ulster)
10 â00 Ronan Oâ00Gara (Cork Constitution/Munster)
9 â00 Eoin Reddan (Wasps)
1 â00 Marcus Horan (Shannon/Munster)
2 â00 Jerry Flannery (Shannon/Munster)
3 â00 John Hayes (Bruff/Munster)
4 â00 Donncha Oâ00Callaghan (Cork Constitution/Munster)
5 â00 Paul Oâ00Connell (Young Munster/Munster)
6 â00 Simon Easterby (Llanelli)
7 â00 David Wallace (Garryowen/Munster)
8 â00 Denis Leamy (Cork Constitution/Munster)
16 â00 Frankie Sheahan (Cork Constitution/Munster)
17 â00 Simon Best (Belfast Harlequins/Ulster)
18 â00 Malcolm Oâ00Kelly (St.Maryâ00s College/Leinster)
19 â00 Neil Best (Belfast Harlequins/Ulster)
20 â00 Isaac Boss (Ballymena/Ulster)
21 â00 Paddy Wallace (Ballymena/Ulster)
22 â00 Gavin Duffy (Galwegians/Connacht)