Ireland's campaign has been solid with two good wins over Scotland and Italy at home but the loss to Wales last weekend will have been disappointing to John O'Sullivan and his charges, who know they are well capable of bettering their Celtic counterparts.
For this weekend's game, O'Sullivan has reverted, for the most part, back to his tried and tested starting fifteen having experimented with some positions against Wales last week.
Tania Rosser, who started at number 10 in that game, reverts back to her more familiar position at scrum half with Richmond's Joanne O'Sullivan sliding across the back-line into out-half from centre.
The talented utility back will face a number of her club mates in Sunbury this Saturday with Richmond providing four players to the English matchday squad.
Aware of his team's challenge, Irish coach O'Sullivan said: "We know we have a very tough task ahead of us in England this weekend. At the moment they are probably the best side in the world but in saying that we are really looking forward to the challenge.
"We were very disappointed, as a squad, with our performance against Wales and know that we are capable of much better which we hope to see this weekend."
England have named an experienced team. Head coach Gary Street has made six changes to the team that beat Scotland and said his team are taking nothing for granted.
"I was surprised to see Ireland lose to Wales. I have been impressed with what they have been doing over the years so one disappointing defeat is not going to change my opinion of them," he said.
"This is the last game of the championship and it's their chance to claim a major scalp. They'll certainly be out to make a statement."
IRELAND WOMEN'S TEAM & REPLACEMENTS (v England, RBS Women's Six Nations, Saturday, March 15, London Irish ARFC, Sunbury, kick-off 4.45pm):
Sarahjane Belton (capt); Lynne Cantwell, Patrique Kelly, Shannon Houston, Grace Davitt; Joanne O'Sullivan, Tania Rosser; Fiona Coghlan, Jess Limbert, Marie Barrett, Caroline Mahon, Germaine Healy, Eimear O'Sullivan, Orla Brennan, Joy Neville.
Replacements: Gillian Bourke, Yvonne Nolan, Sinead Ryan, Louise Austin, Louise Beamish, Niamh Briggs, Amy Davis.