However, Edinburgh scored a double over the Ulstermen last season and the only win in their last nine trips to Ireland was in Belfast last November.
The action continues on Saturday evening with Munster looking to take top spot when Glasgow Warriors are the first visitors to the revamped Thomond Park Stadium.
Interestingly, the only defeat for Munster at home in their last eight games came last May against Glasgow.
The final game of the round will see Leinster, smarting from a home defeat to Munster last Sunday, in Galway to face a Connacht side who have lost their last 13 league games against Irish opposition.
They have not beaten Leinster for nearly four years - losing eight in-a-row to the Dublin-based outfit.
MAGNERS LEAGUE - ROUND 5 FIXTURES:
Friday, October 3 -
Ulster v Edinburgh, Ravenhill, 7.30pm
Saturday, October 4 -
Munster v Glasgow Warriors, Thomond Park Stadium, 7pm (live Setanta Sports Ireland)
Sunday, October 5 -
Connacht v Leinster, The Sportsground, 6pm (live Setanta Sports Ireland)