Robbie Kydd, Sean Lamont, Graeme Morrison, Hugo Southwell, Craig Hamilton and Alastair Kellock will make their senior international debuts in the run-on side.
And fellow debutants Stephen Cranston, Gareth Morton and Scott MacLeod have been named on the replacements' bench.
The Scottish team, prepared by former NSW coach Matt Williams, also includes two Australian-raised players in centre Ben Hinshelwood and hooker Rob Russell.
"We're here to win," coach Matt Williams said.
"It's a long process but these players are well on their way. I'm sure Queensland will be putting out their strongest team and we're ready to face that."
The Scots, who play two Tests against the Wallabies in Melbourne and Sydney next month, failed to win a match in this year's Six Nations. Their last Test win was in a World Cup pool match last year against Fiji, and that was only achieved in the final minutes.
The Wallabies beat them 33-16 in a Brisbane quarter-final.
The Reds finished their Super 12 campaign with three successive victories and their Wallabies squad contingent of Chris Latham, Elton Flatley, Wendell Sailor, John Roe and Nathan Sharpe are all available.
Scotland: Robbie Kydd; Sean Lamont, Ben Hinshelwood, Graeme Morrison, Hugo Southwell; Gordon Ross, Mike Blair (captain); Donnie Macfadyen, Jon Petrie, Andy Hall; Alastair Kellock, Craig Hamilton; Allan Jacobsen, Rob Russell, Craig Smith. Replacements: Steve Scott, Joel Brannigan, Scott MacLeod, Cameron Mather, Graeme Beveridge, Stephen Cranston, Gareth Morton.
AFP - 2004.
