In the forwards there is a new-look front row, with Brett Wilkinson and Ronan Loughney teaming up with Sean Cronin at hooker.
And Michael McCarthy and Andrew Farley start once again in the second row.
Meanwhile, the Connacht Branch will have a second car park open at Galway Community College, Moneenageisha, for the Connacht v Leinster match.
Signage will be placed at both sides of the Moneenageisha roundabout directing cars to this car park.
This car park will opens from 4.30pm next Sunday and will close one hour after the final whistle.
CONNACHT (v Leinster): Fionn Carr; Liam Bibo, Gavin Duffy, Keith Matthews, Mike Roberts; Ian Keatley, Frank Murphy; Brett Wilkinson, Sean Cronin, Ronan Loughney, Michael McCarthy, Andrew Farley, John Muldoon (capt), Johnny O'Connor, Colm Rigney.
Replacements: Conor Muldoon, Robbie Morris, Andrew Browne, Michael Swift, Kieran Campbell, Troy Nathan, John Hearty.