The bench includes Tom Gleeson, Dave Foley and Duncan Williams, who are all in line for their first appearances of the campaign.
Friday night will be a night of firsts. The match is Munster's first home game of the season, their first time wearing the new adidas home kit, it also marks a first Munster outing for South African prop BJ Botha and the first use of the new Musgrave Park stand.
Match tickets are available to purchase online here, from the ticket offices in Cork (Tramore Road) and Limerick (Thomond Park), and the Munster Rugby Stores (Maylor Street, Cork and O'Connell Street, Limerick).
MUNSTER (v London Wasps): Scott Deasy; Doug Howlett, Danny Barnes, Lifeimi Mafi, Simon Zebo; Declan Cusack, Peter Stringer; Wian du Preez, Mike Sherry, BJ Botha, Billy Holland, Ian Nagle, David O'Callaghan, Peter O'Mahony, Paddy Butler.
Replacements (from): Denis Fogarty, Stephen Archer, Marcus Horan, Dave Foley, Tommy O'Donnell, James Coughlan, Duncan Williams, Tom Gleeson, Sean Scanlon, JJ Hanrahan.