Saturday's double header at the Aviva Stadium will see the Ireland Women's squad follow Brian O'Driscoll into the record books when they line out in the first Women's international to be played at the Dublin 4 ground.
The Ireland Women are still in contention to successfully their Six Nations crown despite suffering a 17-10 defeat to England at Twickenham. Check out some photos of the girls in green in action last Saturday night.
The Ireland Women's Sevens squad faced South American opposition in their final two games at the Brazil Sevens tournament in São Paulo, with a 17-12 play-off victory over Argentina confirming them as 11th place finishers.
Having beaten England for the first time last year, the Ireland Women will now look for a repeat result away from home as they take their Six Nations title defence to Twickenham for an eagerly-awaited televised clash.
Laura Lee Walsh scored her first try for the Ireland Women's Sevens team and Elaine Ryan and Aisling Naughton both made their debuts during the pool stages of the Brazil Sevens tournament in São Paulo.
Ireland will field two more debutants, Aisling Naughton and Elaine Ryan, when they take part in the Brazil Sevens in São Paulo over the next two days, which is the third leg of the IRB Women's Sevens World Series.
Ireland's lynchpin centre Lynne Cantwell says the Women's squad are 'really enjoying' the build-up to their next two outings at Twickenham and the Aviva Stadium, instead of taking it as added pressure.
Ireland Women's Sevens head coach Jon Skurr believes the experience of playing the likes of New Zealand and England in Atlanta will stand to his young and inexperienced squad as the IRB Women's Sevens World Series progresses.