Fireworks are guaranteed in Friday night's Cork derby between Highfield and Sunday's Well, while struggling Cashel and Belfast Harlequins are hoping to upset the form book against high-flying Banbridge and Blackrock respectively.
Three of Division 2B's top five clubs are away from home this weekend, so expect some movement in the table. It is third against second as Dungannon and unbeaten Greystones meet in the pick of the round 5 games.
Table-topping Rainey, who make the trip to Sligo, will be aiming to pick up where they left off before the break, while Seapoint and Boyne get the 'Friday Night Lights' treatment this week in a juicy Leinster derby.
Queen's University and Tullamore posted wins in last Saturday's two rescheduled Ulster Bank League games, with the Belfast students climbing into fourth place in Division 2A and the Offaly men now lying second in the 2C table.
Rainey Old Boys are still the team to catch after the opening four rounds of Ulster Bank League Division 2C. Midleton lead the chasing pack, with Bruff becoming the tenth and final team to open their win account.
After a very eventful opening month in Ulster Bank League Division 1A, Old Belvedere have edged their way to the top of the table - closely followed by promoted Dublin University and one of the beaten semi-finalists from last year, Young Munster.